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Generation of a Pain Memory in the Primary Afferent Nociceptor Triggered by PKCε Activation of CPEB

Isolectin B(4)-positive [IB(4)(+)] primary afferent nociceptors challenged with an inflammatory or neuropathic insult develop a PKCε-dependent long-lasting hyperalgesic response to a subsequent challenge by the proinflammatory cytokine prostaglandin E(2) (PGE(2)), a phenomenon known as hyperalgesic...

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Bibliografski detalji
Glavni autori: Bogen, Oliver, Alessandri-Haber, Nicole, Chu, Carissa, Gear, Robert W., Levine, Jon D.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305286/
https://ncbi.nlm.nih.gov/pubmed/22323716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5138-11.2012
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