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An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation

Microglia and astrocytes play essential roles in the maintenance of homeostasis within the central nervous system, but mechanisms that control the magnitude and duration of responses to infection and injury remain poorly understood. Here, we provide evidence that 5-androsten-3β,17β-diol (ADIOL) func...

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Detalhes bibliográficos
Main Authors: Saijo, Kaoru, Collier, Jana G., Li, Andrew C., Katzenellenbogen, John A., Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433492/
https://ncbi.nlm.nih.gov/pubmed/21565615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.050
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