CD86 and IL-12p70 Are Key Players for T Helper 1 Polarization and Natural Killer Cell Activation by Toll-Like Receptor-Induced Dendritic Cells

BACKGROUND: Dendritic cells (DCs) determine the activation and polarization of T cells via expression of costimulatory molecules and secretion of cytokines. The function of DCs derived from monocytes ex vivo strongly depends on the composition of the maturation cocktail used. METHODOLOGY/PRINCIPAL F...

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Библиографические подробности
Главные авторы: Lichtenegger, Felix S., Mueller, Katharina, Otte, Bettina, Beck, Barbara, Hiddemann, Wolfgang, Schendel, Dolores J., Subklewe, Marion
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433478/
https://ncbi.nlm.nih.gov/pubmed/22962607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044266
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