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Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission

BACKGROUND: Active dendritic cell (DC) immunization protocols are rapidly gaining interest as therapeutic options in patients with acute myeloid leukemia (AML). Here we present for the first time a GMP-compliant 3-day protocol for generation of monocyte-derived DCs using different synthetic Toll-lik...

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Detalhes bibliográficos
Main Authors: Beck, Barbara, Dörfel, Daniela, Lichtenegger, Felix S, Geiger, Christiane, Lindner, Lysann, Merk, Martina, Schendel, Dolores J, Subklewe, Marion
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182913/
https://ncbi.nlm.nih.gov/pubmed/21910911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-151
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