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Purified Neonatal Plasmacytoid Dendritic Cells Overcome Intrinsic Maturation Defect with TLR Agonist Stimulation

Neonates are more susceptible than adults to viral and bacterial diseases. We hypothesized that plasmacytoid dendritic cells, the cells that provide large amounts of IFN-α in response to Toll-like receptor 9 (TLR9) agonists, are defective in neonates. To assess the intrinsic functionality of plasmac...

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Detalhes bibliográficos
Main Authors: GOLD, MARIELLE C., DONNELLY, ERIN, COOK, MATTHEW S., LECLAIR, CATHERINE M., LEWINSOHN, DEBORAH A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369427/
https://ncbi.nlm.nih.gov/pubmed/16690948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/01.pdr.0000220352.13547.f4
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