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Purified Neonatal Plasmacytoid Dendritic Cells Overcome Intrinsic Maturation Defect with TLR Agonist Stimulation
Neonates are more susceptible than adults to viral and bacterial diseases. We hypothesized that plasmacytoid dendritic cells, the cells that provide large amounts of IFN-α in response to Toll-like receptor 9 (TLR9) agonists, are defective in neonates. To assess the intrinsic functionality of plasmac...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369427/ https://ncbi.nlm.nih.gov/pubmed/16690948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/01.pdr.0000220352.13547.f4 |
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