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Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection

Megakaryocytes (MKs), the platelet precursors, are capable of accumulating DNA greater than a diploid content as part of their cell cycle. MKs have been recognized as mediating fibrosis in a subset of hematologic malignancies, including acute megakaryoblastic leukemia and a subset of myeloproliferat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Papadantonakis, Nikolaos, Matsuura, Shinobu, Ravid, Katya
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433087/
https://ncbi.nlm.nih.gov/pubmed/22767499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-402594
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