The role of hypoxic-inducible factor (HIF1α) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients

OBJECTIVES: Hypoxia-inducible factor (HIF1α) plays an integral role in response to hypoxia, controlling dozens of target genes including aldolaseC (ALDC), an important enzyme in the glycolytic pathway. It also induces angiogenesis, allowing survival and proliferation of cancer cells. The aims of our...

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Autors principals: Mhawech-Fauceglia, Paulette, Wang, Dan, Samrao, Damanzoopinder, Menesses, Teodulo, Godoy, Heidi, Ough, Faith, Lele, Shashikant, Liu, Song, Pejovic, Tanja
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2012
Matèries:
Pathology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432840/
https://ncbi.nlm.nih.gov/pubmed/22923632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2012-001450
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