Pair Box 8 (PAX8) protein expression in high grade, late stage (stages III and IV) ovarian serous carcinoma

OBJECTIVES: Pair-Box 8 (PAX8) is a transcription factor which has been found to be overexpressed in ovarian serous carcinoma (OSC). Silencing PAX8 by using shRNA led to a drop in cell viability in ovarian cancer cell lines, suggesting its use as a targeted therapeutic agent. The prognostic value of...

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Publicado no:Gynecol Oncol
Main Authors: Mhawech-Fauceglia, Paulette, Wang, Dan, Samrao, Damanzoopinder, Godoy, Heidi, Ough, Faith, Liu, Song, Pejovic, Tanja, Lele, Shashikant
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049509/
https://ncbi.nlm.nih.gov/pubmed/22705448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2012.06.012
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