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Pair Box 8 (PAX8) protein expression in high grade, late stage (stages III and IV) ovarian serous carcinoma
OBJECTIVES: Pair-Box 8 (PAX8) is a transcription factor which has been found to be overexpressed in ovarian serous carcinoma (OSC). Silencing PAX8 by using shRNA led to a drop in cell viability in ovarian cancer cell lines, suggesting its use as a targeted therapeutic agent. The prognostic value of...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Gynecol Oncol |
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Κύριοι συγγραφείς: | , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5049509/ https://ncbi.nlm.nih.gov/pubmed/22705448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2012.06.012 |
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