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The role of hypoxic-inducible factor (HIF1α) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients

OBJECTIVES: Hypoxia-inducible factor (HIF1α) plays an integral role in response to hypoxia, controlling dozens of target genes including aldolaseC (ALDC), an important enzyme in the glycolytic pathway. It also induces angiogenesis, allowing survival and proliferation of cancer cells. The aims of our...

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Detalhes bibliográficos
Main Authors: Mhawech-Fauceglia, Paulette, Wang, Dan, Samrao, Damanzoopinder, Menesses, Teodulo, Godoy, Heidi, Ough, Faith, Lele, Shashikant, Liu, Song, Pejovic, Tanja
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432840/
https://ncbi.nlm.nih.gov/pubmed/22923632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2012-001450
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