Organismal regulation of XBP-1-mediated unfolded protein response during development and immune activation

The increased demand on protein folding in the endoplasmic reticulum (ER) during bacterial infection activates the unfolded protein response (UPR). OCTR-1—a G protein-coupled catecholamine receptor expressed in neurons—suppresses innate immunity by downregulating a non-canonical UPR pathway and the...

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Detaylı Bibliyografya
Asıl Yazarlar: Sun, Jingru, Liu, Yiyong, Aballay, Alejandro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Scientific Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432796/
https://ncbi.nlm.nih.gov/pubmed/22791024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.100
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