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Unfolded Protein Response Genes Regulated by CED-1 are Required for Caenorhabditis elegans Innate Immunity

The endoplasmic reticulum (ER) stress response, also known as the unfolded protein response (UPR), has been implicated in the normal physiology of the immune defense and in several disorders including diabetes, cancer, and neurodegenerative disease. Here we show that the apoptotic receptor CED-1 and...

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Detalhes bibliográficos
Main Authors: Haskins, Kylie A., Russell, Jonathan F., Gaddis, Nathan, Dressman, Holly K., Aballay, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517226/
https://ncbi.nlm.nih.gov/pubmed/18606143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.05.006
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