A marker of homologous recombination predicts pathological complete response to neoadjuvant chemotherapy in primary breast cancer

PURPOSE: To assess the prevalence of defective homologous recombination (HR) based DNA repair in sporadic primary breast cancers, examine the clincopathological features that correlate of with defective HR and the relationship with neoadjuvant chemotherapy response. EXPERIMENTAL DESIGN: We examined...

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Bibliografische gegevens
Hoofdauteurs: Graeser, Monika, McCarthy, Afshan, Lord, Christopher J, Savage, Kay, Hills, Margaret, Salter, Janine, Orr, Nicholas, Parton, Marina, Smith, Ian E, Reis-Filho, Jorge S, Dowsett, Mitch, Ashworth, Alan, Turner, Nicholas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432445/
https://ncbi.nlm.nih.gov/pubmed/20802015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1027
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