Group V Secretory Phospholipase A(2) Enhances the Progression of Angiotensin II–Induced Abdominal Aortic Aneurysms but Confers Protection against Angiotensin II–Induced Cardiac Fibrosis in ApoE-Deficient Mice

Abdominal aortic aneurysms (AAAs) and heart failure are complex life-threatening diseases whose etiology is not completely understood. In this study, we investigated whether deficiency of group V secretory phospholipase A(2) (GV sPLA(2)) protects from experimental AAA. The impact of GV sPLA(2) defic...

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Detalhes bibliográficos
Main Authors: Boyanovsky, Boris B., Bailey, William, Dixon, Lauren, Shridas, Preetha, Webb, Nancy R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432434/
https://ncbi.nlm.nih.gov/pubmed/22813854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.05.037
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