Group X Secretory Phospholipase A(2) Regulates the Expression of Steroidogenic Acute Regulatory Protein (StAR) in Mouse Adrenal Glands

We developed C57BL/6 mice with targeted deletion of group X secretory phospholipase A(2) (GX KO). These mice have ∼80% higher plasma corticosterone concentrations compared with wild-type (WT) mice under both basal and adrenocorticotropic hormone (ACTH)-induced stress conditions. This increased corti...

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Autors principals: Shridas, Preetha, Bailey, William M., Boyanovsky, Boris B., Oslund, Rob C., Gelb, Michael H., Webb, Nancy R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888415/
https://ncbi.nlm.nih.gov/pubmed/20421306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.090423
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