Llwytho...

Group X Secretory Phospholipase A(2) Negatively Regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages

OBJECTIVES: Group X secretory phospholipase A(2) (GX sPLA(2)) potently hydrolyzes plasma membranes to generate lysophospholipids and free fatty acids and has been implicated in inflammatory diseases including atherosclerosis. Here we identify a novel role for GX sPLA(2) in modulating ABCA1 and ABCG1...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shridas, Preetha, Bailey, William M, Gizard, Florence, Oslund, Rob C, Gelb, Michael H, Bruemmer, Dennis, Webb, Nancy R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958102/
https://ncbi.nlm.nih.gov/pubmed/20844270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.210237
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!