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Paclitaxel-conjugated PEG and arginine-grafted bioreducible poly (disulfide amine) micelles for co-delivery of drug and gene

We developed a paclitaxel-conjugated polymeric micelle, ABP-PEG(3.5k)-Paclitaxel (APP) consisting of poly (ethylene glycol) (PEG) and arginine-grafted poly(cystaminebisacrylamide-diaminohexane) (ABP) for the co-delivery of gene and drug. The APP polymer self-assembled into cationic polymeric micelle...

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Detalles Bibliográficos
Main Authors: Nam, Kihoon, Nam, Hye Yeong, Kim, Pyung-Hwan, Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432178/
https://ncbi.nlm.nih.gov/pubmed/22871423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.07.031
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