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Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia-reperfusion: therapeutic potential of mitochondrially-targeted antioxidants

Mitochondrial reactive oxygen species generation has been implicated in the pathophysiology of ischemia-reperfusion (I/R) injury, however its exact role and its spatial-temporal relationship with inflammation are elusive. Herein we explored the spatial-temporal relationship of oxidative/nitrative st...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, Partha, Horváth, Bėla, Zsengellėr, Zsuzsanna, Bátkai, Sándor, Cao, Zongxian, Kechrid, Malek, Holovac, Eileen, Erdėlyi, Katalin, Tanchian, Galin, Liaudet, Lucas, Stillman, Isaac E., Joseph, Joy, Kalyanaraman, Balaraman, Pacher, Pál
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432152/
https://ncbi.nlm.nih.gov/pubmed/22683818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.05.036
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