Cisplatin Nephrotoxicity Involves Mitochondrial Injury with Impaired Tubular Mitochondrial Enzyme Activity

Cisplatin is a widely used antineoplastic agent. However, its major limitation is dose-dependent nephrotoxicity whose precise mechanism is poorly understood. Recent studies have suggested that mitochondrial dysfunction in tubular epithelium contributes to cisplatin-induced nephrotoxicity. Here the a...

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Main Authors: Zsengellér, Zsuzsanna K., Ellezian, Lena, Brown, Dan, Horváth, Béla, Mukhopadhyay, Partha, Kalyanaraman, Balaraman, Parikh, Samir M., Karumanchi, S. Ananth, Stillman, Isaac E., Pacher, Pál
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2012
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460350/
https://ncbi.nlm.nih.gov/pubmed/22511597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155412446227
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