Environmental Enrichment Alters Nicotine-Mediated Locomotor Sensitization and Phosphorylation of DARPP-32 and CREB in Rat Prefrontal Cortex

Exposure within an environmental enrichment paradigm results in neurobiological adaptations and decreases the baseline of locomotor activity. The current study determined activation of DARPP-32 (dopamine- and cAMP-regulated phosphoprotein-32) and CREB (cAMP response element binding protein), and loc...

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Autors principals: Gomez, Adrian M., Midde, Narasimha M., Mactutus, Charles F., Booze, Rosemarie M., Zhu, Jun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432100/
https://ncbi.nlm.nih.gov/pubmed/22952905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044149
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