Pharmacokinetics of Peptide Mediated Delivery of Anticancer Drug Ellipticine

The amino acid pairing peptide EAK16-II (EAK) has shown the ability to stabilize the hydrophobic anticancer agent ellipticine (EPT) in aqueous solution. In this study, we investigate pharmacokinetics of the formulation of EAK-EPT complexes in vivo. The developed formulation can achieve a sufficientl...

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Bibliographic Details
Main Authors: Ma, Weina, Lu, Sheng, Pan, Pei, Sadatmousavi, Parisa, Yuan, Yongfang, Chen, P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432029/
https://ncbi.nlm.nih.gov/pubmed/22952737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043684
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