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Pharmacokinetics of Peptide Mediated Delivery of Anticancer Drug Ellipticine
The amino acid pairing peptide EAK16-II (EAK) has shown the ability to stabilize the hydrophobic anticancer agent ellipticine (EPT) in aqueous solution. In this study, we investigate pharmacokinetics of the formulation of EAK-EPT complexes in vivo. The developed formulation can achieve a sufficientl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432029/ https://ncbi.nlm.nih.gov/pubmed/22952737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043684 |
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