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Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo

BACKGROUND AND METHODS: Applications of the anticancer agent, ellipticine, have been limited by its hydrophobicity and toxicity. An efficient delivery system is required to exploit the enormous potential of this compound. Recently, EAK16-II, an ionic-complementary, self-assembling peptide, has been...

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Detalhes bibliográficos
Main Authors: Wu, Yan, Sadatmousavi, Parisa, Wang, Rong, Lu, Sheng, Yuan, Yong-fang, Chen, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396387/
https://ncbi.nlm.nih.gov/pubmed/22802684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S31858
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