A Photocleavable Amphiphilic Prodrug Self-Assembled Nanoparticles with Effective Anticancer Activity In Vitro

Accelerating degradation of prodrug is an effective strategy for improving the pharmacological action. A photocleavable amphiphilic prodrug of methotrexate-coumarin derivative-PEG conjugates (MTX-AMC-PEG) with photo-triggered breakage to release clinical drug under laser irradiation was fabricated a...

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Vydáno v:Nanomaterials (Basel)
Hlavní autoři: Chen, Ji, Li, Guotao, Liu, Qihong, Liang, Yan, Liu, Miaochang, Wu, Huayue, Gao, Wenxia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630543/
https://ncbi.nlm.nih.gov/pubmed/31195730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano9060860
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