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Phosphorylation of the effector complex HOPS by the vacuolar kinase Yck3p confers Rab nucleotide specificity for vacuole docking and fusion

The homotypic fusion of yeast vacuoles requires the Rab-family GTPase Ypt7p and its effector complex, homotypic fusion and vacuole protein sorting complex (HOPS). Although the vacuolar kinase Yck3p is required for the sensitivity of vacuole fusion to proteins that regulate the Rab GTPase cycle—Gdi1p...

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Autors principals: Zick, Michael, Wickner, William
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431944/
https://ncbi.nlm.nih.gov/pubmed/22787280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-04-0279
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