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Improved reconstitution of yeast vacuole fusion with physiological SNARE concentrations reveals an asymmetric Rab(GTP) requirement

In vitro reconstitution of homotypic yeast vacuole fusion from purified components enables detailed study of membrane fusion mechanisms. Current reconstitutions have yet to faithfully replicate the fusion process in at least three respects: 1) The density of SNARE proteins required for fusion in vit...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Zick, Michael, Wickner, William
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985260/
https://ncbi.nlm.nih.gov/pubmed/27385334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-04-0230
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