Identification and Characterization of the Thermus thermophilus 5-Methylcytidine (m(5)C) Methyltransferase Modifying 23 S Ribosomal RNA (rRNA) Base C1942

Methylation of cytidines at carbon-5 is a common posttranscriptional RNA modification encountered across all domains of life. Here, we characterize the modifications of C1942 and C1962 in Thermus thermophilus 23 S rRNA as 5-methylcytidines (m(5)C) and identify the two associated methyltransferases....

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Detalhes bibliográficos
Main Authors: Larsen, Line H. G., Rasmussen, Anette, Giessing, Anders M. B., Jogl, Gerwald, Kirpekar, Finn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431712/
https://ncbi.nlm.nih.gov/pubmed/22711535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.376160
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