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Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5’-methylthio-adenosine
Post-transcriptional modification of ribosomal RNA occurs in all kingdoms of life. The S-adenosyl-L-me-thionine-dependent methyltransferase KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of A1518 and A1519 of 16S rRNA. Loss of this dimethylation confers resis...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679894/ https://ncbi.nlm.nih.gov/pubmed/19285505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.02.066 |
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