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Ring Finger Protein RNF169 Antagonizes the Ubiquitin-dependent Signaling Cascade at Sites of DNA Damage

Ubiquitin signals emanating from DNA double-strand breaks (DSBs) trigger the ordered assembly of DNA damage mediator and repair proteins. This highly orchestrated process is accomplished, in part, through the concerted action of the RNF8 and RNF168 E3 ligases, which have emerged as core signaling in...

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מידע ביבליוגרפי
Main Authors: Chen, Jie, Feng, Wanjuan, Jiang, Jun, Deng, Yiqun, Huen, Michael S. Y.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431699/
https://ncbi.nlm.nih.gov/pubmed/22733822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373530
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