Bone Morphogenetic Protein Signaling in Vascular Disease: ANTI-INFLAMMATORY ACTION THROUGH MYOCARDIN-RELATED TRANSCRIPTION FACTOR A

Pulmonary artery hypertension (PAH) patients exhibit elevated levels of inflammatory cytokines and infiltration of inflammatory cells in the lung. Concurrently, mutations of bmpr2, the gene encoding the type II receptor of bone morphogenetic proteins (BMP), are found in ∼75% of patients with familia...

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Main Authors: Wang, Dahai, Prakash, Jamunabai, Nguyen, Peter, Davis-Dusenbery, Brandi N., Hill, Nicholas S., Layne, Matthew D., Hata, Akiko, Lagna, Giorgio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431673/
https://ncbi.nlm.nih.gov/pubmed/22718766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379487
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