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C3a and C5a Promote Renal Ischemia-Reperfusion Injury
Renal ischemia reperfusion injury triggers complement activation, but whether and how the small proinflammatory fragments C3a and C5a contribute to the pathogenesis of this injury remains to be elucidated. Using C3aR-, C5aR-, or C3aR/C5aR-deficient mice and models of renal ischemia-reperfusion injur...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431410/ https://ncbi.nlm.nih.gov/pubmed/22797180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011111072 |
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