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Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability
The discovery that somatic cells are reprogrammable to pluripotency by ectopic expression of a small subset of transcription factors has created great potential for the development of broadly applicable stem-cell-based therapies. One of the concerns regarding the safe use of induced pluripotent stem...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431347/ https://ncbi.nlm.nih.gov/pubmed/22952451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002913 |
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