Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53

DNA double-strand breaks (DSBs) represent one of the most deleterious forms of DNA damage to a cell. In cancer therapy, induction of cell death by DNA DSBs by ionizing radiation (IR) and certain chemotherapies is thought to mediate the successful elimination of cancer cells. However, cancer cells of...

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Autori principali: Sorrells, Shelly, Carbonneau, Seth, Harrington, Erik, Chen, Aye T., Hast, Bridgid, Milash, Brett, Pyati, Ujwal, Major, Michael B., Zhou, Yi, Zon, Leonard I., Stewart, Rodney A., Look, A. Thomas, Jette, Cicely
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431329/
https://ncbi.nlm.nih.gov/pubmed/22952453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002922
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