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Autocrine Sonic Hedgehog Attenuates Inflammation in Cerulein-Induced Acute Pancreatitis in Mice via Upregulation of IL-10

Hedgehog signaling plays critical roles in pancreatic oncogenesis and chronic pancreatitis, but its roles in acute pancreatitis (AP) are largely ambiguous. In this study, we provide evidence that Sonic hedgehog (Shh), but neither Desert hedgehog (Dhh) nor Indian hedgehog (Ihh), is the main protein w...

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Bibliografske podrobnosti
Main Authors: Zhou, Xiangyu, Liu, Zhiqiang, Jang, Feng, Xiang, Chuannan, Li, Yuan, He, Yanzheng
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431299/
https://ncbi.nlm.nih.gov/pubmed/22956998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044121
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