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Cortactin as a Target for FAK in the Regulation of Focal Adhesion Dynamics

BACKGROUND: Efficient cell movement requires the dynamic regulation of focal adhesion (FA) formation and turnover. FAs are integrin-associated sites of cell attachment and establish linkages to the cellular actin cytoskeleton. Cells without focal adhesion kinase (FAK), an integrin-activated tyrosine...

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Bibliografiske detaljer
Main Authors: Tomar, Alok, Lawson, Christine, Ghassemian, Majid, Schlaepfer, David D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430618/
https://ncbi.nlm.nih.gov/pubmed/22952866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044041
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