Weekly paclitaxel, gemcitabine, and external irradiation followed by randomized farnesyl transferase inhibitor R115777 for locally advanced pancreatic cancer

PURPOSE: The Radiation Therapy Oncology Group (RTOG) multi-institutional Phase II study 98-12, evaluating paclitaxel and concurrent radiation (RT) for locally advanced pancreatic cancer, demonstrated a median survival of 11.3 months and a 1-year survival of 43%. The purpose of the randomized Phase I...

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Main Authors: Rich, Tyvin A, Winter, Kathryn, Safran, Howard, Hoffman, John P, Erickson, Beth, Anne, Pramila R, Myerson, Robert J, Cline-Burkhardt, Vivian JM, Perez, Kimberly, Willett, Christopher
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2012
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430391/
https://ncbi.nlm.nih.gov/pubmed/22977306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S33560
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