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AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2
AU-rich elements (AREs), present in mRNA 3′-UTRs, are potent posttranscriptional regulatory signals that can rapidly effect changes in mRNA stability and translation, thereby dramatically altering gene expression with clinical and developmental consequences. In human cell lines, the TNFα ARE enhance...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430382/ https://ncbi.nlm.nih.gov/pubmed/17382880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.01.038 |
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