A specialized mechanism of translation mediated by FXR1a-associated microRNP in cellular quiescence

MicroRNAs predominantly decrease gene expression; however, specific mRNAs are translationally upregulated in quiescent (G0) mammalian cells and immature Xenopus laevis oocytes by an FXR1a-associated microRNP (microRNA-protein complex) that lacks the microRNP repressor, GW182. Their mechanism in thes...

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Gepubliceerd in:Mol Cell
Hoofdauteurs: Bukhari, Syed I.A., Truesdell, Samuel S., Lee, Sooncheol, Kollu, Swapna, Classon, Anthony, Boukhali, Myriam, Jain, Esha, Mortensen, Richard D., Yanagiya, Akiko, Sadreyev, Ruslan I., Haas, Wilhelm, Vasudevan, Shobha
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811377/
https://ncbi.nlm.nih.gov/pubmed/26942679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.02.013
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