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Effect of treatment in vivo with N,N-dimethylnitrosamine or methyl methanesulphonate on the cytoplasmic DNA polymerase of regenerating rat liver.

A 10-16 fold increase in rat liver cytoplasmic DNA polymerase (DNA polymerase-alpha) was observed by 24 hrs after two thirds partial hepatectomy. Injection of either N,N-dimethylnitrosamine (DMN) or methyl methanesulphonate (MMS) At 6 or 12 hrs after partial hepatectomy completely inhibited this inc...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Salisbury, J G, O'Connor, P J
Format: Artigo
Language:Inglês
Published: Oxford University Press 1976
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343013/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/183185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/3.6.1561
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