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Comparative Studies of the Hepatocarcinogen N,N-Dimethylnitrosamine in vivo: Reaction Sites in Rat Liver DNA and the Significance of their Relative Stabilities

The reaction of the hepatocarcinogen N,N-dimethylnitrosamine has been compared with that of methyl methanesulphonate, a methylating agent which is not a liver carcinogen. Consistent differences have been observed in the reaction of rat liver DNA in vivo with these agents; O(6)-alkylation and the pro...

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Detalhes bibliográficos
Main Authors: O'Connor, P. J., Capps, M. J., Craig, A. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2008841/
https://ncbi.nlm.nih.gov/pubmed/4694387
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