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Predicting effects of structural stress in a genome-reduced model bacterial metabolism

Mycoplasma pneumoniae is a human pathogen recently proposed as a genome-reduced model for bacterial systems biology. Here, we study the response of its metabolic network to different forms of structural stress, including removal of individual and pairs of reactions and knockout of genes and clusters...

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Bibliografiske detaljer
Main Authors: Güell, Oriol, Sagués, Francesc, Serrano, M. Ángeles
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429883/
https://ncbi.nlm.nih.gov/pubmed/22934134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00621
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