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Predicting effects of structural stress in a genome-reduced model bacterial metabolism

Mycoplasma pneumoniae is a human pathogen recently proposed as a genome-reduced model for bacterial systems biology. Here, we study the response of its metabolic network to different forms of structural stress, including removal of individual and pairs of reactions and knockout of genes and clusters...

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Autors principals: Güell, Oriol, Sagués, Francesc, Serrano, M. Ángeles
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429883/
https://ncbi.nlm.nih.gov/pubmed/22934134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00621
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