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Metabolic plasticity in synthetic lethal mutants: Viability at higher cost
The most frequent form of pairwise synthetic lethality (SL) in metabolic networks is known as plasticity synthetic lethality. It occurs when the simultaneous inhibition of paired functional and silent metabolic reactions or genes is lethal, while the default of the functional partner is backed up by...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5806928/ https://ncbi.nlm.nih.gov/pubmed/29381693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005949 |
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