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Specific release of ribosomal proteins by nucleic acid-intercalating agents.
Increasing concentrations of ethidium bromide cause progressive inactivation of ribosomes, apparently by binding to double-stranded regions of the rRNA. At low drug concentrations (10(-4)M) the partial inhibition detected is due to specific release of proteins L7 and L12; activity can be restored by...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1976
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342988/ https://ncbi.nlm.nih.gov/pubmed/781624 |
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