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Ditosylate Salt of Itraconazole and Dissolution Enhancement Using Cyclodextrins
Salt formation has been a promising approach for improving the solubility of poorly soluble acidic and basic drugs. The aim of the present study was to prepare the salt form of itraconazole (ITZ), a hydrophobic drug to improve the solubility and hence dissolution performance. Itraconazolium ditolene...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer US
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429683/ https://ncbi.nlm.nih.gov/pubmed/22669594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9804-5 |
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