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Ditosylate Salt of Itraconazole and Dissolution Enhancement Using Cyclodextrins

Salt formation has been a promising approach for improving the solubility of poorly soluble acidic and basic drugs. The aim of the present study was to prepare the salt form of itraconazole (ITZ), a hydrophobic drug to improve the solubility and hence dissolution performance. Itraconazolium ditolene...

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Bibliografski detalji
Glavni autori: Kumar, Neeraj, Shishu, Bansal, Gulshan, Kumar, Sandeep, Jana, Asim Kumar
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429683/
https://ncbi.nlm.nih.gov/pubmed/22669594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9804-5
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