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Enhanced Dissolution and Stability of Lansoprazole by Cyclodextrin Inclusion Complexation: Preparation, Characterization, and Molecular Modeling

In this study, lansoprazole (LSP)/cyclodextrin (CD) inclusion complexes were prepared using a fluid bed coating technique, with β-cyclodextrin (β-CD) and 2-hydroxypropyl-β-cyclodextrin (HPCD) as the host molecules, respectively, to simultaneously improve the dissolution and stability of LSP. The dis...

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Detalhes bibliográficos
Main Authors: Lu, Yi, Guo, Tao, Qi, Jianping, Zhang, Jiwen, Wu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513431/
https://ncbi.nlm.nih.gov/pubmed/22968546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9842-z
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