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Targeting the tumor mutanome for personalized vaccination therapy
Next generation sequencing enables identification of immunogenic tumor mutations targetable by individualized vaccines. In the B16F10 melanoma system as pre-clinical proof-of-concept model, we found a total of 563 non-synonymous expressed somatic mutations. Of the mutations we tested, one third were...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429589/ https://ncbi.nlm.nih.gov/pubmed/22934277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19727 |
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