The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis

Vav1 is expressed exclusively in hematopoietic cells and is required for T cell development and activation. Vav1-deficient mice show thymic hypocellularity due to a partial block during thymocyte development at the DN3 stage and between the double positive (DP) and single positive (SP) transition. V...

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Bibliographic Details
Main Authors: Kaminski, Sandra, Adjali, Oumeya, Jacquet, Chantal, Garaude, Johan, Keriel, Anne, Lassaux, Adeline, Hipskind, Robert, Sitbon, Marc, Taylor, Naomi, Villalba, Martin
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429564/
https://ncbi.nlm.nih.gov/pubmed/22934252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20225
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