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Influence of Target Concentration and Background Binding on In Vitro Selection of Affinity Reagents
Nucleic acid-based aptamers possess many useful features that make them a promising alternative to antibodies and other affinity reagents, including well-established chemical synthesis, reversible folding, thermal stability and low cost. However, the selection process typically used to generate apta...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429449/ https://ncbi.nlm.nih.gov/pubmed/22952815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043940 |
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