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Elevating SOX2 Levels Deleteriously Affects the Growth of Medulloblastoma and Glioblastoma Cells

Medulloblastomas and glioblastomas are devastating tumors that respond poorly to treatment. These tumors have been shown to express SOX2 and overexpression of SOX2 has been correlated with poor prognosis. Although knockdown of SOX2 impairs the growth and tumorigenicity of brain tumor cells, it was u...

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Bibliografische gegevens
Hoofdauteurs: Cox, Jesse L., Wilder, Phillip J., Desler, Michelle, Rizzino, Angie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429438/
https://ncbi.nlm.nih.gov/pubmed/22937156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044087
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